BDBM50036540 CHEMBL3353598

SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)cc1)c1ncc(cc1Cl)C(F)(F)F

InChI Key InChIKey=WECUMEJQVKOERZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036540   

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Raqualia Pharma

Curated by ChEMBL

LigandBDBM50036540(CHEMBL3353598)Copy SMILESCopy InChI

Affinity DataIC50: 40nMAssay Description:Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as inhibition of menthol induced Ca2+ influxMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/15/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Raqualia Pharma

Curated by ChEMBL

LigandBDBM50036540(CHEMBL3353598)Copy SMILESCopy InChI

Affinity DataIC50: 43nMAssay Description:Antagonist activity at rat TRPM8 assessed as inhibition of menthol induced Ca2+ influx by cell-based assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/15/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL