BDBM50036517 CHEMBL3353597

SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc(cc1Cl)C(F)(F)F

InChI Key InChIKey=IJGQFZYYEHCCIZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50036517   

LigandPNGBDBM50036517(CHEMBL3353597)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandPNGBDBM50036517(CHEMBL3353597)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandPNGBDBM50036517(CHEMBL3353597)
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as inhibition of menthol induced Ca2+ influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandPNGBDBM50036517(CHEMBL3353597)
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at rat TRPM8 assessed as inhibition of menthol induced Ca2+ influx by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandPNGBDBM50036517(CHEMBL3353597)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced Ca2+ influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandPNGBDBM50036517(CHEMBL3353597)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced Ca2+ influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandPNGBDBM50036517(CHEMBL3353597)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human TRPV4 expressed in HEK293 cells assessed as inhibition of hypotonic solution-induced Ca2+ influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
LigandPNGBDBM50036517(CHEMBL3353597)
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed