BDBM50036436 4-(8-Chloro-5-isopropylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine::CHEMBL163239

SMILES [#6]-[#7]-1-[#6]-[#6]-[#6](=[#6]-[#6]-1)-[#6]-1=[#6]-c2ccccc2\[#6](=[#6](/[#6])-[#6])-c2ccc(Cl)cc-12

InChI Key InChIKey=DWBMEQFUDHRGOJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50036436   

TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50036436(4-(8-Chloro-5-isopropylidene-5H-dibenzo[a,d]cycloh...)
Affinity DataKi:  100nMAssay Description:Ability to inhibit the binding of [3H]spiperone to the Dopamine receptor D4 in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50036436(4-(8-Chloro-5-isopropylidene-5H-dibenzo[a,d]cycloh...)
Affinity DataKi:  440nMAssay Description:Ability to inhibit the binding of [3H]spiperone to the Dopamine receptor D2L in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50036436(4-(8-Chloro-5-isopropylidene-5H-dibenzo[a,d]cycloh...)
Affinity DataKi:  760nMAssay Description:Ability to inhibit the binding of iodine-125-labelled lysergic acid diethylamide([125I]-LSD) to the S-2A serotonin receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50036436(4-(8-Chloro-5-isopropylidene-5H-dibenzo[a,d]cycloh...)
Affinity DataKi:  1.20E+3nMAssay Description:Ability to inhibit the binding of iodine-125-labelled lysergic acid diethylamide([125I]-LSD) to the S-2C serotonin receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed