BDBM50036382 (Z)-6-[2-(1-Methyl-1-p-tolyloxy-ethyl)-4-pyridin-3-yl-[1,3]dioxan-5-yl]-hex-4-enoic acid::CHEMBL350595

SMILES Cc1ccc(OC(C)(C)C2OCC(C\C=C/CCC(O)=O)C(O2)c2cccnc2)cc1

InChI Key InChIKey=MUBWANKZYHXEGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036382   

TargetProstacyclin synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036382((Z)-6-[2-(1-Methyl-1-p-tolyloxy-ethyl)-4-pyridin-3...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036382((Z)-6-[2-(1-Methyl-1-p-tolyloxy-ethyl)-4-pyridin-3...)
Affinity DataIC50: 360nMAssay Description:In vitro Inhibition of thromboxane synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed