BDBM50036370 (Z)-6-{2-[1-(4-Cyano-phenoxy)-1-methyl-ethyl]-4-pyridin-3-yl-[1,3]dioxan-5-yl}-hex-4-enoic acid::CHEMBL161357

SMILES CC(C)(Oc1ccc(cc1)C#N)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1

InChI Key InChIKey=HFMOTQLJYSDUDP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036370   

TargetProstacyclin synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036370((Z)-6-{2-[1-(4-Cyano-phenoxy)-1-methyl-ethyl]-4-py...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036370((Z)-6-{2-[1-(4-Cyano-phenoxy)-1-methyl-ethyl]-4-py...)
Affinity DataIC50: 46nMAssay Description:In vitro Inhibition of thromboxane synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed