BDBM50036363 (Z)-6-[2-(3,4-Dichloro-phenyl)-4-pyridin-3-yl-[1,3]dioxan-5-yl]-hex-4-enoic acid::CHEMBL422719

SMILES OC(=O)CC\C=C/CC1COC(OC1c1cccnc1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=IXVZMIJUOSLLMR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036363   

TargetThromboxane-A synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036363((Z)-6-[2-(3,4-Dichloro-phenyl)-4-pyridin-3-yl-[1,3...)
Affinity DataIC50: 42nMAssay Description:In vitro Inhibition of thromboxane synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036363((Z)-6-[2-(3,4-Dichloro-phenyl)-4-pyridin-3-yl-[1,3...)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed