BDBM50036358 (Z)-6-[2-(2-Cyano-phenyl)-4-pyridin-3-yl-[1,3]dioxan-5-yl]-hex-4-enoic acid::CHEMBL161104

SMILES OC(=O)CC\C=C/CC1COC(OC1c1cccnc1)c1ccccc1C#N

InChI Key InChIKey=SMPANMCXFZXSLU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036358   

TargetProstacyclin synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036358((Z)-6-[2-(2-Cyano-phenyl)-4-pyridin-3-yl-[1,3]diox...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036358((Z)-6-[2-(2-Cyano-phenyl)-4-pyridin-3-yl-[1,3]diox...)
Affinity DataIC50: 54nMAssay Description:In vitro Inhibition of thromboxane synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed