BDBM50036350 2-{1-[5-((Z)-5-Carboxy-pent-2-enyl)-4-pyridin-3-yl-[1,3]dioxan-2-yl]-1-methyl-ethoxy}-benzoic acid methyl ester::CHEMBL159344

SMILES COC(=O)c1ccccc1OC(C)(C)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1

InChI Key InChIKey=BLQRRTMBZPZHCY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036350   

TargetProstacyclin synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036350(2-{1-[5-((Z)-5-Carboxy-pent-2-enyl)-4-pyridin-3-yl...)
Affinity DataIC50: 7.30E+4nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036350(2-{1-[5-((Z)-5-Carboxy-pent-2-enyl)-4-pyridin-3-yl...)
Affinity DataIC50: 66nMAssay Description:In vitro Inhibition of thromboxane synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed