BDBM50036299 CHEMBL3353058

SMILES ONC(=O)c1cc2CN(CCn2c1)C(=O)C1CCCCC1

InChI Key InChIKey=IRYNPILZVVOIKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036299   

TargetHistone deacetylase 6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036299(CHEMBL3353058)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant N-GST-tagged HDAC6 (unknown origin) assessed as reduction in deacetylation of Ac-Arg-Gly-Lys(Ac)-AMC substrate by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036299(CHEMBL3353058)
Affinity DataIC50: 730nMAssay Description:Inhibition of HDAC6 in human HeLa cells assessed as reduction in K40 hyperacetylation of alpha-tubulin incubated for 6 hrs by immunofluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed