BDBM50036287 CHEMBL345247::N-[5-(4,5-Dimethyl-isoxazol-3-ylsulfamoyl)-naphthalen-1-yl]-acetamide

SMILES CC(=O)Nc1cccc2c(cccc12)S(=O)(=O)Nc1noc(C)c1C

InChI Key InChIKey=MYPMATSTUPRQRI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036287   

TargetEndothelin-1 receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50036287(N-[5-(4,5-Dimethyl-isoxazol-3-ylsulfamoyl)-naphtha...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [125I]endothelin-l binding to endothelin A receptor of rat thoracic aorta smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed