BDBM50036222 (1Z)-prop-1-ene-1,2,3-tricarboxylic acid::(Z)-1-propene-1,2,3-tricarboxylic acid::CHEMBL347285::cis-1-propene-1,2,3-tricarboxylic acid::cis-aconitic acid

SMILES OC(=O)C\C(=C\C(O)=O)C(O)=O

InChI Key InChIKey=GTZCVFVGUGFEME-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50036222   

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50036222((1Z)-prop-1-ene-1,2,3-tricarboxylic acid | cis-aco...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50036222((1Z)-prop-1-ene-1,2,3-tricarboxylic acid | cis-aco...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036222((1Z)-prop-1-ene-1,2,3-tricarboxylic acid | cis-aco...)
Affinity DataKi: >1.00E+6nMAssay Description:Reversible binding potential for rat ATP-Citrate Lyase as carbon-carbon bond cleavage activity in citrate substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed