BDBM50036088 CHEMBL18734::[(6S,13S)-13-(3-Guanidino-propyl)-14-methyl-6,9,12,15-tetraoxo-6,7,8,9,10,11,12,13,14,15-decahydro-5H-20,21-dithia-5,8,11,14-tetraaza-dibenzo[a,e]cycloheptadecen-7-yl]-acetic acid::[(7S,13S)-13-(3-Guanidino-propyl)-14-methyl-6,9,12,15-tetraoxo-6,7,8,9,10,11,12,13,14,15-decahydro-5H-20,21-dithia-5,8,11,14-tetraaza-dibenzo[a,e]cycloheptadecen-7-yl]-acetic acid::[13-(3-Guanidino-propyl)-14-methyl-6,9,12,15-tetraoxo-6,7,8,9,10,11,12,13,14,15-decahydro-5H-20,21-dithia-5,8,11,14-tetraaza-dibenzo[a,e]cycloheptadecen-7-yl]-acetic acid (SK&F 107260)

SMILES CN1[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccccc2SSc2ccccc2C1=O

InChI Key InChIKey=YITSCMGHJOGUNC-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50036088   

TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036088([(6S,13S)-13-(3-Guanidino-propyl)-14-methyl-6,9,12...)
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]-SKF- 107260 binding to purified alphaIIb-beta3 integrin of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036088([(6S,13S)-13-(3-Guanidino-propyl)-14-methyl-6,9,12...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036088([(6S,13S)-13-(3-Guanidino-propyl)-14-methyl-6,9,12...)
Affinity DataKi:  2.80nMAssay Description:Affinity for platelet fibrinogen receptor, integrin alpha IIb/beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036088([(6S,13S)-13-(3-Guanidino-propyl)-14-methyl-6,9,12...)
Affinity DataKi:  3.5nMAssay Description:Affinity for vitronectin receptor, integrin alphaV-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036088([(6S,13S)-13-(3-Guanidino-propyl)-14-methyl-6,9,12...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of binding to alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036088([(6S,13S)-13-(3-Guanidino-propyl)-14-methyl-6,9,12...)
Affinity DataKi:  4.5nMAssay Description:Dissociation constant for platelet glycoprotein alphaIIb-beta3 integrin from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article