BDBM50035956 5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid (3-propylamino-propyl)-amide::CHEMBL335492

SMILES CCCNCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F

InChI Key InChIKey=LERGQFAABXNVDV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50035956   

TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035956(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of arachidonic acid-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035956(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of collagen-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035956(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed