BDBM50035786 4-Amino-1-((3R,5R)-5-hydroxymethyl-tetrahydro-thiophen-3-yl)-1H-pyrimidin-2-one::CHEMBL132049

SMILES Nc1ccn([C@H]2CS[C@@H](CO)C2)c(=O)n1

InChI Key InChIKey=VZFZUTKQULGQJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035786   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50035786(4-Amino-1-((3R,5R)-5-hydroxymethyl-tetrahydro-thio...)
Affinity DataIC50: 355nMAssay Description:Ability to inhibit the HIV-1 reverse transcriptase in cord blood mononuclear cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed