BDBM50035785 4-Amino-1-((2S,5R)-5-hydroxymethyl-tetrahydro-thiophen-2-yl)-1H-pyrimidin-2-one::CHEMBL129094

SMILES Nc1ccn([C@@H]2CC[C@H](CO)S2)c(=O)n1

InChI Key InChIKey=LAQKYFKORDKGFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035785   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50035785(4-Amino-1-((2S,5R)-5-hydroxymethyl-tetrahydro-thio...)
Affinity DataIC50: 287nMAssay Description:Ability to inhibit the HIV-1 reverse transcriptase in cord blood mononuclear cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed