BDBM50035673 CHEMBL2377796

SMILES NS(=O)(=O)c1ccc(CN2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1

InChI Key InChIKey=QANGVWSVBMPVJM-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50035673   

TargetProstaglandin G/H synthase 1(Sheep)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50035673(CHEMBL2377796)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX1-mediated prostaglandin alpha production by enzyme immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50035673(CHEMBL2377796)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX2-mediated prostaglandin alpha production by enzyme immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50035673(CHEMBL2377796)
Affinity DataKi:  0.690nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50035673(CHEMBL2377796)
Affinity DataKi:  3.10nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50035673(CHEMBL2377796)
Affinity DataKi:  3.10nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50035673(CHEMBL2377796)
Affinity DataKi:  5.20nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50035673(CHEMBL2377796)
Affinity DataKi:  427nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed