BDBM50035636 CHEMBL108960::[(1S,2S,4R)-1-Benzyl-2-hydroxy-4-((1S,2R)-2-hydroxy-indan-1-ylcarbamoyl)-4-methyl-5-phenyl-pentyl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@@](C)(Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12

InChI Key InChIKey=DMZUPOFDIRSBAO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50035636   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035636([(1S,2S,4R)-1-Benzyl-2-hydroxy-4-((1S,2R)-2-hydrox...)
Affinity DataIC50: 7.70nMAssay Description:In vitro inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035636([(1S,2S,4R)-1-Benzyl-2-hydroxy-4-((1S,2R)-2-hydrox...)
Affinity DataIC50: 7nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035636([(1S,2S,4R)-1-Benzyl-2-hydroxy-4-((1S,2R)-2-hydrox...)
Affinity DataIC50: 7.80nMAssay Description:Inhibitory activity against HIV-1 protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035636([(1S,2S,4R)-1-Benzyl-2-hydroxy-4-((1S,2R)-2-hydrox...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human immunodeficiency virus type 1 (HIV-1) protease enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed