BDBM50035635 CHEMBL322984::[(1S,2S,4R)-1-Benzyl-4-((1S,2S,3R)-2,3-dihydroxy-indan-1-ylcarbamoyl)-2-hydroxy-7-phenyl-heptyl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@@H](CCCc1ccccc1)C(=O)N[C@@H]1[C@H](O)[C@H](O)c2ccccc12

InChI Key InChIKey=BNEUUKYSHWONFU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035635   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035635([(1S,2S,4R)-1-Benzyl-4-((1S,2S,3R)-2,3-dihydroxy-i...)
Affinity DataIC50: 0.190nMAssay Description:In vitro inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035635([(1S,2S,4R)-1-Benzyl-4-((1S,2S,3R)-2,3-dihydroxy-i...)
Affinity DataIC50: 0.190nMAssay Description:Inhibitory activity against HIV-1 protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed