BDBM50035276 5-((2,5-diethoxyphenylamino)methyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::5-[(2,5-Diethoxy-phenylamino)-methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::CHEMBL69363

SMILES CCOc1ccc(OCC)c(NCc2c[nH]c3nc(N)nc(N)c23)c1

InChI Key InChIKey=BSBNJEWMFGLQLW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50035276   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035276(5-((2,5-diethoxyphenylamino)methyl)-7H-pyrrolo[2,3...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035276(5-((2,5-diethoxyphenylamino)methyl)-7H-pyrrolo[2,3...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035276(5-((2,5-diethoxyphenylamino)methyl)-7H-pyrrolo[2,3...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035276(5-((2,5-diethoxyphenylamino)methyl)-7H-pyrrolo[2,3...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035276(5-((2,5-diethoxyphenylamino)methyl)-7H-pyrrolo[2,3...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed