BDBM50035162 CHEMBL3343163

SMILES FC(F)(F)c1nnc(NC(=O)C(=C\c2cn(Cc3ccccc3)c3ccccc23)\C#N)s1

InChI Key InChIKey=CONJDOYMPQAENJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035162   

TargetGenome polyprotein(Dengue virus 2)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50035162(CHEMBL3343163)
Affinity DataKd:  9.27E+3nMAssay Description:Binding affinity to Dengue virus 2 NS2B/NS3 protease by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus 2)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50035162(CHEMBL3343163)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of Dengue virus 2 NS2B/NS3 protease using Bz-Nle-Lys-Arg-Arg-AMC as substrate preincubated for 30 mins before substrate addition by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed