BDBM50035150 1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}-5-methylspiro[1,3-dihydroisobenzofuran-1,4'-(hexahydropyridine)]::CHEMBL64115

SMILES Cc1ccc2c(COC22CCN(CCCCc3cn(-c4ccc(F)cc4)c4ccccc34)CC2)c1

InChI Key InChIKey=DCLIJJMBPKSDOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035150   

TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035150(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}-5-me...)
Affinity DataIC50: 2.30nMAssay Description:Binding affinity towards Sigma receptor type 2 in whole rat brain homogenates except cerebellum using radioligand ([3H]DTG) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035150(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}-5-me...)
Affinity DataIC50: 9.5nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed