BDBM50035042 1-Benzofuran-7-yl-piperazine::CHEMBL61032

SMILES C1CN(CCN1)c1cccc2ccoc12

InChI Key InChIKey=KFVKNZPFYQDNAE-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50035042   

Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035042(1-Benzofuran-7-yl-piperazine | CHEMBL61032)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035042(1-Benzofuran-7-yl-piperazine | CHEMBL61032)
Affinity DataKi:  13nMAssay Description:Displacement of radioligand [3H]2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035042(1-Benzofuran-7-yl-piperazine | CHEMBL61032)
Affinity DataKi:  13nMAssay Description:Binding affinity was evaluated by determining in vitro displacement of [3H]8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition sit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035042(1-Benzofuran-7-yl-piperazine | CHEMBL61032)
Affinity DataKi:  13nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50035042(1-Benzofuran-7-yl-piperazine | CHEMBL61032)
Affinity DataKi:  780nMAssay Description:In vitro displacement of [3H]spiperone from Dopamine receptor D2 binding site in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed