BDBM50034808 CHEMBL3353011

SMILES [H][C@]12CC[C@](CO)(C[C@H]1n1cnc3c(N)ncnc13)C2

InChI Key InChIKey=JHMDCTCOXQJTFX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50034808   

TargetPhosphatidylinositol 4-kinase type 2-alpha(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50034808(CHEMBL3353011)
Affinity DataIC50: 4.89E+4nMAssay Description:Inhibition of human PI4K2alpha expressed in Escherichia coli BL21 after 60 mins by ADP-GloTM Kinase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase type 2-alpha(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50034808(CHEMBL3353011)
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of PI4K2A catalytic domain (unknown origin) assessed as enzyme residual activity incubated for 60 mins using ATP as substrate by ATP-Glo l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4-kinase alpha(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50034808(CHEMBL3353011)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PI4KA catalytic domain (unknown origin) assessed as enzyme residual activity incubated for 60 mins using ATP as substrate by ATP-Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50034808(CHEMBL3353011)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PI4KB catalytic domain (unknown origin) assessed as enzyme residual activity incubated for 60 mins using ATP as substrate by ATP-Glo lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed