BDBM50034468 4-Benzylamino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL25730

SMILES Cc1noc(NS(=O)(=O)c2ccc(NCc3ccccc3)cc2)c1C

InChI Key InChIKey=HADQVLLXWGMTEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034468   

TargetEndothelin-1 receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034468(4-Benzylamino-N-(3,4-dimethyl-isoxazol-5-yl)-benze...)
Affinity DataIC50: 9.80E+3nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034468(4-Benzylamino-N-(3,4-dimethyl-isoxazol-5-yl)-benze...)
Affinity DataIC50: 9.80E+3nMAssay Description:Ability to inhibit [125I]ET1 binding to vascular smooth muscle (vsm)- A10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed