BDBM50034449 5-Amino-naphthalene-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL25756

SMILES Cc1noc(NS(=O)(=O)c2ccc3c(N)cccc3c2)c1C

InChI Key InChIKey=HTJPEVDLBKGUQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034449   

TargetEndothelin-1 receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034449(5-Amino-naphthalene-2-sulfonic acid (3,4-dimethyl-...)
Affinity DataIC50: 2.40E+4nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034449(5-Amino-naphthalene-2-sulfonic acid (3,4-dimethyl-...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of [125I]endothelin-l binding to endothelin A receptor of rat thoracic aorta smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed