BDBM50034441 5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalene-1-carboxylic acid::CHEMBL30246

SMILES Cc1noc(NS(=O)(=O)c2cccc3c(cccc23)C(O)=O)c1C

InChI Key InChIKey=XZVLKLYTZGMQQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034441   

TargetEndothelin-1 receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034441(5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalen...)
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034441(5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalen...)
Affinity DataIC50: 1.30E+4nMAssay Description:Ability to inhibit [125I]ET1 binding to vascular smooth muscle (vsm)- A10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed