BDBM50034365 CHEMBL554220::Trifluoro-methanesulfonic acid (R)-7-propylamino-5,6,7,8-tetrahydro-naphthalen-2-yl ester; hydrochloride

SMILES CCCN[C@@H]1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1

InChI Key InChIKey=YIJDPVLWVKAIMO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50034365   

TargetD(2) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034365(Trifluoro-methanesulfonic acid (R)-7-propylamino-5...)
Affinity DataKi:  50nMAssay Description:In vitro binding affinity towards dopamine D2 receptor by using [3H]U-86170 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034365(Trifluoro-methanesulfonic acid (R)-7-propylamino-5...)
Affinity DataKi:  125nMAssay Description:In vitro binding affinity towards 5-HT1D alpha receptor by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034365(Trifluoro-methanesulfonic acid (R)-7-propylamino-5...)
Affinity DataKi:  222nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034365(Trifluoro-methanesulfonic acid (R)-7-propylamino-5...)
Affinity DataKi:  340nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1D receptor alpha by using [3H]-5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034365(Trifluoro-methanesulfonic acid (R)-7-propylamino-5...)
Affinity DataKi:  359nMAssay Description:In vitro binding affinity towards Dopamine receptor D3 by using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed