BDBM50034000 3-(1-Benzyl-piperidin-4-yl)-1-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-propan-1-one; hydrochloride::CHEMBL1196495::CHEMBL557181

SMILES O=C(CCC1CCN(Cc2ccccc2)CC1)c1ccc2OCCOc2c1

InChI Key InChIKey=ZCUGLCPNDXQRDS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50034000   

TargetAcetylcholinesterase(Human)
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50034000(CHEMBL1196495 | CHEMBL557181 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 30.2nMAssay Description:Inhibition of human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034000(CHEMBL1196495 | CHEMBL557181 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 4.80E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50034000(CHEMBL1196495 | CHEMBL557181 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 30nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed