BDBM50033930 (R)-2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-3-(4-nitro-phenyl)-propionic acid::CHEMBL268629

SMILES Cc1nc2ccc(CN(CC#C)c3ccc(cc3)C(=O)N[C@H](Cc3ccc(cc3)[N+]([O-])=O)C(O)=O)cc2c(=O)[nH]1

InChI Key InChIKey=NXVYTJAGYKNPAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033930   

TargetThymidylate synthase(Mouse)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033930((R)-2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50: 42nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed