BDBM50033909 CHEMBL6590::N-Furan-3-ylmethyl-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzamide

SMILES Cc1nc2ccc(CN(CC#C)c3ccc(cc3)C(=O)NCc3ccoc3)cc2c(=O)[nH]1

InChI Key InChIKey=SJCOVOXWSZPSOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033909   

TargetThymidylate synthase(Mouse)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033909(N-Furan-3-ylmethyl-4-[(2-methyl-4-oxo-3,4-dihydro-...)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed