BDBM50033899 CHEMBL264095::N-(3-Cyano-benzyl)-4-[(2,7-dimethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-benzamide

SMILES Cc1nc2cc(C)c(CN(CC#C)c3ccc(C(=O)NCc4cccc(c4)C#N)c(F)c3)cc2c(=O)[nH]1

InChI Key InChIKey=IJZWNCOLMNECHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033899   

TargetThymidylate synthase(Mouse)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033899(N-(3-Cyano-benzyl)-4-[(2,7-dimethyl-4-oxo-3,4-dihy...)
Affinity DataIC50: 48nMAssay Description:Ability to inhibit Thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed