BDBM50033782 4-Ethyl-7-[6-fluoro-7-methyl-2-oxo-1,2-dihydro-indol-(3E)-ylidene]-4-hydroxy-1,4,7,8-tetrahydro-pyrano[3,4-f]indolizine-3,6,10-trione::CHEMBL173820

SMILES CCC1(O)C(=O)OCc2c1cc1C(=O)\C(Cn1c2=O)=C1\C(=O)Nc2c1ccc(F)c2C

InChI Key InChIKey=SFTGOKOOQOOBTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033782   

TargetDNA topoisomerase 1(Human)
Glaxo Research Institute

Curated by ChEMBL
LigandPNGBDBM50033782(4-Ethyl-7-[6-fluoro-7-methyl-2-oxo-1,2-dihydro-ind...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine topoisomerase I, using cleavable complex assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed