BDBM50033779 (R)-4-Ethyl-4-hydroxy-7-[5-methyl-7-nitro-2-oxo-1,2-dihydro-indol-(3E)-ylidene]-1,4,7,8-tetrahydro-pyrano[3,4-f]indolizine-3,6,10-trione::CHEMBL367649

SMILES CC[C@]1(O)C(=O)OCc2c1cc1C(=O)\C(Cn1c2=O)=C1\C(=O)Nc2c1cc(C)cc2[N+]([O-])=O

InChI Key InChIKey=IIEZWWXBZMHQBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033779   

TargetDNA topoisomerase 1(Human)
Glaxo Research Institute

Curated by ChEMBL
LigandPNGBDBM50033779((R)-4-Ethyl-4-hydroxy-7-[5-methyl-7-nitro-2-oxo-1,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine topoisomerase I, using cleavable complex assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed