BDBM50033772 CHEMBL354432::ethyl 8-ethyl-8-hydroxy-9,12-dioxo-2,3,8,9,12,14-hexahydro-11H-[1,4]dioxino[2,3-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-15-carboxylate

SMILES CCOC(=O)c1c2Cn3c(cc4c(COC(=O)C4(O)CC)c3=O)-c2nc2cc3OCCOc3cc12

InChI Key InChIKey=PSWVBLIRMZQLSV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033772   

TargetDNA topoisomerase 1(Human)
Glaxo Research Institute

Curated by ChEMBL
LigandPNGBDBM50033772(ethyl 8-ethyl-8-hydroxy-9,12-dioxo-2,3,8,9,12,14-h...)
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration against topoisomerase I obtained from calf thymusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed