BDBM50033653 1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-17-yl]-4-(4-nitrophenyl)-(Z)-2-butenamide::CHEMBL317035

SMILES Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)C=C[C@@]35NC(=O)C=Cc1ccc(cc1)[N+]([O-])=O

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033653   

TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50033653(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50: 11nMAssay Description:Binding affinity against kappa opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50033653(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50: 106nMAssay Description:Binding affinity against delta opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50033653(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50: 7.80nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed