BDBM50033588 CHEMBL3358114

SMILES CN1CCC(CCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)N(C(F)F)c2c(C)nn(C)c2C)CC1

InChI Key InChIKey=HLJCVRXGZMOFDS-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50033588   

TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50033588(CHEMBL3358114)
Affinity DataIC50: 12nMAssay Description:Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50033588(CHEMBL3358114)
Affinity DataIC50: 600nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50033588(CHEMBL3358114)
Affinity DataIC50: 12nMAssay Description:Inhibition of human NMT1 using [3H]-myristoyl-coA/biotinylated CAP5.5 as substrate after 15 mins by scintillation/luminescence counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2019
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
State University of Paraiba

Curated by ChEMBL
LigandPNGBDBM50033588(CHEMBL3358114)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
State University of Paraiba

Curated by ChEMBL
LigandPNGBDBM50033588(CHEMBL3358114)
Affinity DataKi:  0.340nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed