BDBM50033544 6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-tetrahydro-quinazoline-2,4-diamine::CHEMBL121348

SMILES CN(CC1CCc2nc(N)nc(N)c2C1)c1cccc2ccccc12

InChI Key InChIKey=GUIFHQSZBXGPLV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50033544   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033544(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-...)
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033544(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033544(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-...)
Affinity DataIC50: 47nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033544(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033544(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033544(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-...)
Affinity DataIC50: 47nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed