BDBM50033541 6-[(3,4-Dichloro-phenylamino)-methyl]-5,6,7,8-tetrahydro-quinazoline-2,4-diamine::CHEMBL120994

SMILES Nc1nc(N)c2CC(CNc3ccc(Cl)c(Cl)c3)CCc2n1

InChI Key InChIKey=QOFUANCNUPCYME-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50033541   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033541(6-[(3,4-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033541(6-[(3,4-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033541(6-[(3,4-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033541(6-[(3,4-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 150nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033541(6-[(3,4-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033541(6-[(3,4-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed