BDBM50033296 Benzyl-(2-phenyl-quinazolin-4-yl)-amine::CHEMBL72650

SMILES C(Nc1nc(nc2ccccc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=WXCHSHPXEPXKFN-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50033296   

LigandPNGBDBM50033296(Benzyl-(2-phenyl-quinazolin-4-yl)-amine | CHEMBL72...)
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50033296(Benzyl-(2-phenyl-quinazolin-4-yl)-amine | CHEMBL72...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of rat brain Phosphodiesterase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50033296(Benzyl-(2-phenyl-quinazolin-4-yl)-amine | CHEMBL72...)
Affinity DataKi:  7.90E+3nMAssay Description:Displacement of [125I]RTI-55 from Dopamine transporter of rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50033296(Benzyl-(2-phenyl-quinazolin-4-yl)-amine | CHEMBL72...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]RTI-55 binding to Serotonin transporter of rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed