BDBM50033290 Benzyl-(2-imidazol-1-yl-quinazolin-4-yl)-amine::CHEMBL118944

SMILES C(Nc1nc(nc2ccccc12)-n1ccnc1)c1ccccc1

InChI Key InChIKey=FNTPEBIGZTYDQK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033290   

LigandPNGBDBM50033290(Benzyl-(2-imidazol-1-yl-quinazolin-4-yl)-amine | C...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Biofor

Curated by ChEMBL
LigandPNGBDBM50033290(Benzyl-(2-imidazol-1-yl-quinazolin-4-yl)-amine | C...)
Affinity DataIC50: 220nMAssay Description:In vitro inhibition of Thromboxane A2 synthase in human plateletMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50033290(Benzyl-(2-imidazol-1-yl-quinazolin-4-yl)-amine | C...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat brain Phosphodiesterase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed