BDBM50033079 4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid::CHEMBL96184

SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(=C)c1ccc(cc1)C(O)=O

InChI Key InChIKey=SPARUJQOIBYQHO-UHFFFAOYSA-N

Data  6 KI  6 Kd  14 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50033079   

TargetRetinoic acid receptor gamma(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  266nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetRetinoic acid receptor RXR-beta(Mouse)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKd:  199nMAssay Description:Inhibition of [3H]9-cis-RA binding to baculovirus expressed retinoid receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against retinoid receptor isoform (RAR alpha) expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-gamma(Mouse)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  404nMAssay Description:Effective concentration against retinoid receptor isoform (RXR gamma) expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKd:  909nMAssay Description:Inhibition of [3H]ATRA binding to baculovirus expressed retinoid receptor RAR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKd:  150nMAssay Description:Inhibition of [3H]9-cis-RA binding to baculovirus expressed retinoid receptor RXR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  266nMAssay Description:Effective concentration against retinoid receptor isoform (RAR gamma) expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  39nMAssay Description:Effective concentrations against Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  2nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  270nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-gamma(Mouse)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKd:  290nMAssay Description:Inhibition of [3H]9-cis-RA binding to baculovirus expressed retinoid receptor RXR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Mouse)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  486nMAssay Description:Effective concentration against retinoid receptor isoform (RXR beta) expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  304nMAssay Description:Effective concentration against retinoid receptor isoform (RAR beta) expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKd:  944nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed retinoid receptor RAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  409nMAssay Description:Effective concentration against retinoid receptor isoform (RXR alpha) expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKd:  887nMAssay Description:Tested for binding affinity against [3H]-ATRA binding to retinoid receptor isoform (RAR gamma) expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  404nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetRetinoic acid receptor beta(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  304nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetRetinoic acid receptor RXR-alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  409nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetRetinoic acid receptor RXR-beta(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  486nMAssay Description:Inhibition of [3H]9-cis-RA binding to RXR beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetRetinoic acid receptor RXR-alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKi:  150nMAssay Description:Inhibition of [3H]9-cis-RA binding to RXR alpha receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetRetinoic acid receptor RXR-beta(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKi:  199nMAssay Description:Inhibition of [3H]9-cis-RA binding to RXR beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetRetinoic acid receptor RXR-gamma(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKi:  290nMAssay Description:Inhibition of [3H]9-cis-RA binding to RXR gamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetRetinoic acid receptor gamma(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKi:  887nMAssay Description:Inhibition of [3H]ATRA binding to RAR gamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetRetinoic acid receptor beta(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKi:  909nMAssay Description:Inhibition of [3H]ATRA binding to RAR beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetRetinoic acid receptor alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKi:  944nMAssay Description:Inhibition of [3H]ATRA binding to RAR alpha receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article