BDBM50032911 CHEMBL1535485

SMILES COc1cccc(c1)C(=O)Nc1ccc2n(C)c(=O)n(C)c2c1

InChI Key InChIKey=HKTKWXDSSQNEDD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50032911   

TargetPeregrin(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50032911(CHEMBL1535485)
Affinity DataIC50: 3.16E+3nMAssay Description:Binding affinity to 6H-Flag-tagged Tev-BRPF1 (622-738 aa) (unknown origin) by TR-FRET competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50032911(CHEMBL1535485)
Affinity DataIC50: 1.58E+4nMAssay Description:Binding affinity to 6His-tagged-BRD4 BD1 Y390A mutant (1 to 477 aa) (unknown origin) by TR-FRET competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50032911(CHEMBL1535485)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged BRD4 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed