BDBM500329 (6'-Hydroxy-8'-oxo-8'H-spiro[cyclopentane-1,5'-indolizine]-7'-carbonyl)glycine ethyl ester (10)::US11021478, Example 10::US11655249, Example 10

SMILES CCOC(=O)CNC(=O)C1=C(O)C2(CCCC2)n2cccc2C1=O

InChI Key InChIKey=FSZYLKRZFZLKAA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 500329   

TargetEgl nine homolog 1(Human)
Kind Pharmaceutical

US Patent
LigandPNGBDBM500329(US11021478, Example 10 | (6'-Hydroxy-8'-oxo-8'H-sp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Activities of HIF prolyl hydroxylase was determined according to the method as described in Anal Biochem, 2004, 330: 74-80, which was slightly modifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
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TargetEgl nine homolog 1(Human)
Kind Pharmaceutical

US Patent
LigandPNGBDBM500329(US11021478, Example 10 | (6'-Hydroxy-8'-oxo-8'H-sp...)
Affinity DataIC50: 1.00E+4nMAssay Description:1. Effect of Compounds on Activities of HIF Prolyl Hydroxylase-2 Activities of HIF prolyl hydroxylase was determined according to the method as descr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
Go to US Patent