BDBM50032750 CHEMBL3355181

SMILES Clc1ccccc1NC(=O)Nc1cnn(c1)-c1cccc(c1)C(=O)NCC1CCNCC1

InChI Key InChIKey=XDNOBDTYZKRSTK-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50032750   

TargetMitogen-activated protein kinase 10(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032750(CHEMBL3355181)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of JNK3 in human SH-SY5Y cells assessed as reduction in c-Jun phosphorylation by Western blot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032750(CHEMBL3355181)
Affinity DataIC50: 206nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032750(CHEMBL3355181)
Affinity DataIC50: 311nMAssay Description:Inhibition of JNK2 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032750(CHEMBL3355181)
Affinity DataIC50: 206nMAssay Description:Inhibition of recombinant human full-length JNK3 using ATF2 as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032750(CHEMBL3355181)
Affinity DataIC50: 311nMAssay Description:Inhibition of human JNK2alpha2 using ATF2 as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50032750(CHEMBL3355181)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human JNK1alpha1 using ATF2 as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032750(CHEMBL3355181)
Affinity DataIC50: 311nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032750(CHEMBL3355181)
Affinity DataIC50: 206nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed