BDBM50032695 CHEMBL3354673

SMILES O=C(Nc1ccc2cc[nH]c2c1)c1c[nH]c2ccccc2c1=O

InChI Key InChIKey=XPRGZRFECLBYKZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50032695   

LigandPNGBDBM50032695(CHEMBL3354673)
Affinity DataEC50:  100nMAssay Description:Corrector activity at CFTR mutant (unknown origin) by phenotypic screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032695(CHEMBL3354673)
Affinity DataEC50:  100nMAssay Description:Potentiation of human CFTR F508del mutant expressed in mouse NIH-3T3 cells after 30 mins by fluorescent voltage sensing optical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
LigandPNGBDBM50032695(CHEMBL3354673)
Affinity DataEC50:  100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed