BDBM50032694 CHEMBL3354672

SMILES O=C(N(Cc1ccccc1)Cc1ccccc1)c1c[nH]c2ccccc2c1=O

InChI Key InChIKey=XBEAXEHFZLGHEG-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50032694   

LigandPNGBDBM50032694(CHEMBL3354672)
Affinity DataEC50:  2.10E+3nMAssay Description:Corrector activity at CFTR mutant (unknown origin) by phenotypic screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50032694(CHEMBL3354672)
Affinity DataEC50:  2.10E+3nMAssay Description:Potentiation of human CFTR F508del mutant expressed in mouse NIH-3T3 cells after 30 mins by fluorescent voltage sensing optical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
LigandPNGBDBM50032694(CHEMBL3354672)
Affinity DataEC50:  2.10nMAssay Description:Inhibition of CFTR F508 deletion mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
LigandPNGBDBM50032694(CHEMBL3354672)
Affinity DataEC50:  2.10E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed