BDBM50032601 CHEMBL3354172

SMILES CCn1c(NC2CCCC2)nc2c(csc2c1=O)C#CCN1CCOCC1

InChI Key InChIKey=HVXLYTLVGVKSCK-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032601   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Kyoto 607-8042

Curated by ChEMBL

LigandBDBM50032601(CHEMBL3354172)Copy SMILESCopy InChI

Affinity DataIC50: 19nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/12/2016
Entry Details Article
Copy BDB DOIPubMed
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyoto 607-8042

Curated by ChEMBL

LigandBDBM50032601(CHEMBL3354172)Copy SMILESCopy InChI

Affinity DataIC50: 820nMAssay Description:Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/12/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL