BDBM50032533 (2S,3S)-3-(4-Chloro-phenyl)-2-ethyl-8-methyl-8-aza-bicyclo[3.2.1]octane::CHEMBL27336

SMILES CC[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2C

InChI Key

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50032533   

LigandPNGBDBM50032533((2S,3S)-3-(4-Chloro-phenyl)-2-ethyl-8-methyl-8-aza...)
Affinity DataIC50: 2.60nMAssay Description:Inhibitory concentration against [3H]dopamine uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM50032533((2S,3S)-3-(4-Chloro-phenyl)-2-ethyl-8-methyl-8-aza...)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]mazindol from dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSodium-dependent dopamine transporter(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50032533((2S,3S)-3-(4-Chloro-phenyl)-2-ethyl-8-methyl-8-aza...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50032533((2S,3S)-3-(4-Chloro-phenyl)-2-ethyl-8-methyl-8-aza...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed