BDBM50032526 17-allyl-4-hydroxy-3,10-dimethoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::CHEMBL317030

SMILES COc1c(O)ccc2CC3N(CC=C)CCC4(CC(=O)CC[C@@]34OC)c12

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50032526   

TargetMu-type opioid receptor(Guinea pig)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50032526(17-allyl-4-hydroxy-3,10-dimethoxy-17-azatetracyclo...)
Affinity DataKi:  7.30nMAssay Description:Binding affinity was evaluated by measuring the ability to displace [3H]DAMGO radioligand binding from Opioid receptor mu 1 in guinea pig brain membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50032526(17-allyl-4-hydroxy-3,10-dimethoxy-17-azatetracyclo...)
Affinity DataKi:  25nMAssay Description:In vivo binding affinity was evaluated by measuring the ability to displace [3H]U-69593 radioligand binding from Opioid receptor kappa 1 in guinea pi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50032526(17-allyl-4-hydroxy-3,10-dimethoxy-17-azatetracyclo...)
Affinity DataKi:  26nMAssay Description:In vivo binding affinity was evaluated by measuring the ability to displace [3H]DPDPE radioligand binding from delta opioid receptor in guinea pig br...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed