BDBM50032454 CHEMBL3354147::US9353075, 44

SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(cc1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=UCQSXFHFXRBIKX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50032454   

TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
University of California

US Patent
LigandPNGBDBM50032454(US9353075, 44 | CHEMBL3354147)
Affinity DataIC50: 24nMpH: 7.4Assay Description:Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent

TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
University of California

US Patent
LigandPNGBDBM50032454(US9353075, 44 | CHEMBL3354147)
Affinity DataIC50: 28nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
University of California

US Patent
LigandPNGBDBM50032454(US9353075, 44 | CHEMBL3354147)
Affinity DataIC50: 27.5nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed